What is CRISPR?

In this video Paul Andersen explains how the CRISPR/Cas immune system was identified in bacteria and how the CRISPR/Cas9 system was developed to edit genomes.

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Music Attribution

Intro
Title: I4dsong_loop_main.wav
Artist: CosmicD
Link to sound: http://www.freesound.org/peopl....e/CosmicD/sounds/725
Creative Commons Atribution License

Outro
Title: String Theory
Artist: Herman Jolly
http://sunsetvalley.bandcamp.c....om/track/string-theo

All of the images are licensed under creative commons and public domain licensing:
Adenosine. (2009). English: Artistic rendering of a T4 bacteriophage. The colours grey and orange do not signify anything, they are just used to illustrate structure. Created for Wikipedia. Retrieved from https://commons.wikimedia.org/....wiki/File:PhageExter
E. coli Bacteria. (n.d.). Retrieved February 17, 2016, from https://www.flickr.com/photos/niaid/16598492368/
Fioretti, B. F. Hallbauer &. (2015). English: Director, Max Planck Institute for Infection Biology, Department of Regulation in Infection Biology. Visiting professor The Laboratory for Molecular Infection Medicine Sweden MIMS; http://www.mpiib-berlin.mpg.de..../research/regulation Retrieved from https://commons.wikimedia.org/....wiki/File:Emmanuelle
Foresman, P. S. ([object HTMLTableCellElement]). English: Line art drawing of a chimera. Retrieved from https://commons.wikimedia.org/....wiki/File:Chimera_(P
Magladem96. (2014). English: Picture of DNA Base Flipping. Retrieved from https://commons.wikimedia.org/....wiki/File:Dna-base-f
project, C. wiki. (2014). English: Crystal Structure of Cas9 bound to DNA based on the Anders et al 2014 Nature paper. Rendition was performed using UCSF’s chimera software. Retrieved from https://commons.wikimedia.org/....wiki/File:Cas9_Ander
Providers, P. C. (1979). English: Photomicrograph of Streptococcus pyogenes bacteria, 900x Mag. A pus specimen, viewed using Pappenheim’s stain. Last century, infections by S. pyogenes claimed many lives especially since the organism was the most important cause of puerperal fever and scarlet fever. Streptococci. Retrieved from https://commons.wikimedia.org/....wiki/File:Streptococ
RRZEicons. (2010). English: zipper, open, close. Retrieved from https://commons.wikimedia.org/wiki/File:Zipper.svg
UC Berkeley. (n.d.). Gene editing with CRISPR-Cas9. Retrieved from https://www.youtube.com/watch?v=avM1Yg5oEu0